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Insulin and hypertension

Source: Writer: Date:2008-04-03 Tag: Hits:
Insulin and hypertension
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In recent years, insulin and hypertension caused the relationship between the medical profession and widespread concern. Observed that patients with hypertension fasting insulin levels were significantly higher than normal. Hyperinsulinemia led to the mechanism of high blood pressure there are several hypotheses:
 
① hyperinsulinemia may renal reabsorption of sodium to the role of enhanced, resulting in water and sodium Lu, increased blood pressure by increased blood volume;
 
② sodium floods due to stay through the sodium-calcium exchange of intracellular calcium concentration increased vascular resistance increased而使prompted a rise in blood pressure;
 
③ human blood glucose levels normal, hyperinsulinemia can increase the excitement of the sympathetic nervous system, so that higher blood pressure;
 
④ high insulin inhibited the synthesis of PGI2, resulting in peripheral vascular resistance caused by increased blood pressure.
 
Hyperinsulinemia also accompanied with high triglyceride hyperlipidemia, and low high-density lipoprotein levels, and often are more common in obese body. However, not all hyperinsulinemia who have hypertension. Not all hypertension patients have high levels of insulin, the relationship between the two need to be to continue to study.